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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Bovine papillomavirus ： ウィキペディア英語版 Bovine papillomavirus Bovine papillomavirus (BPV) is a group of DNA viruses of the family ''Papillomaviridae'' that are common in cattle. Infection causes warts (papillomas and fibropapillomas) of the skin and alimentary tract, and more rarely cancers of the alimentary tract and urinary bladder. They are also thought to cause the skin tumour equine sarcoid in horses and donkeys. BPV provides an excellent model for studying papillomavirus molecular biology, and also allows the dissection of the processes by which this group of viruses cause cancer. ==Structure and genetic organisation== Like other papillomaviruses, BPVs are small non-enveloped viruses with an icosahedral capsid around 50–60 nm in diameter.〔Shah KV, Howley PM. 'Papillomaviruses' in ''Fields Virology'' (3rd edn) (Fields BN, Knipe DM, Howley PM, ''et al.'', eds), Lippincott-Raven Publishers, Philadelphia, 1996〕〔(Campo, MS. 'Bovine papillomavirus: old system, new lessons?'. In ''Papillomavirus Research: From Natural History to Vaccine and Beyond'', Campo, MS (ed), Caister Academic Press (2006) )〕 The capsid is formed of the L1 and L2 structural proteins, with the L1 C-terminus exposed.〔〔(Modis Y, Trus BL, Harrison SC. (2002) Atomic model of the papillomavirus capsid. ''EMBO J'' 21:4754-4762 )〕 All BPVs have a circular double-stranded DNA genome of 7.3–8.0 kb. The genetic organisation of those BPVs which have been sequenced is broadly similar to other papillomaviruses. The open reading frames (ORFs) are all located on one strand, and are divided into early and late regions. The early region encodes nonstructural proteins E1 to E7. There are three viral oncoproteins, E5, E6 and E7; BPVs of the ''Xipapillomavirus'' group lack E6. The late region encodes structural proteins L1 and L2. There is also a non-coding long control region (LCR).〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Bovine papillomavirus」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.